Adrenocorticotropic Hormone Stimulation Test

By | يونيو 5, 2014

:Normal range

(Cortisol, baseline: > 5mg/dL (>138 nmol/L*

(After Cortisol: Peak response: > 20 mg/dL (> 552 nmol/L*

Comment: This is screening test only. Normal (positive) response rules out primary and overt secondary adrenal insufficiency, but a partial ACTH deficiency is not excluded. A sub-normal response indicates decreased adrenal reserve and a diagnosis of insufficiency, either primary adrenal failure (e.g. Addison’s disease) or secondary pituitary disease, or suppression by steroid medications. To distinguish primary and secondary insufficiency, the prolonged ACTH tests and plasma ACTH measurements maybe performed. In adrenal hyperplasia, there is 3-to-5 fold increase. In adrenal Carcinoma, there is little or no response

Sample: Serum