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Normal range: Negative

Comment: Used to evaluate adrenal insufficiency and Addison’s disease. Serum antibodies to adrenal cortical cells, usually of all three zones, are seen in 60 % of patients with idiopathic Addison’s disease. They are also present in patients with fungal, tuberculous, or metastatic destruction of the adrenals. Antiadrenal antibodies can be present in idiopathic hypoparathyroidism and Hashimoto disease

Sample: serum