:Normal range
10-18 wk: 209 Pg/ml 46 pmol/L
26-30 wk: 430 Pg/ml 95 pmol/L
35-36 wk: 162 Pg/ml 36 pmol/L
Comment: ACTH in amniotic fluid is decreased in anencephalic fetuses. ACTH may also be of fetal origin. The relatively high concentration of ACTH in the normal fetus my reflect immaturity and hypothalamic regulation
Sample: Amniotic fluid, under ice