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Normal range: Negative

Comment: Epstein Barr virus is a DNA virus that infects mostly young children and adolescence. But is does infect adults not infrequently. The virus enters the human body system through the oropharyngeal epithelial and lymphoid tissue. The virus enters the cell DNA and incorporate into the cell and may induce oncogenic changes in some of the cells later in life

:Antibodies response

Viral capsid antigen (VCA): IgM and IgG: first to rise in the incubation period and prodromal phase. IgM falls after 2nd and 3rd week. IgG: remains during life

EBV nuclear antigen antibody (EBNA): rises during the later portion of the convalescence (after 2 weeks) and detectable throughout life

Early antigen-Diffuse type: EA-D: rises with onset of clinical symptoms and decreased after 9-10 months. It is also increased during reactivation of the disease and is considered usually as a marker of reactivation of infection

Sample: serum