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Introduction: This is a cell surface glycoprotein, strongly expressed in mesothelial cells, benign or malignant

:Clinical Use

-1

Confirming the diagnosis of Mesothelioma ( the only marker available as positive confirmation

-2 Identying atypical cells in the body fluid (e.g: pleural or peritoneal fluid) whether of mesothelial origin or

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(very helpful in identifying metastatic carcinoma from atypical reactive mesothelial cells)

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