Normal range: 15-60 ng/mL
Comment: 1,25OH vitamin D is particularly useful in evaluating patients with hypercalcemia due to extrarenal conversion of 25OH vitamin D to 1,25OH vitamin
D (calcitriol). Such a situation occurs in sarcoidosis, cat-scratch disease, and certain Mega Moolah er ratoff!Mega Joker er en norsk klassiker som du kan teste her! Spill en av de beste norske spilleautomater idag. lymphomas. These patients have increased levels of 1.25OH vitamin D. The underlying biochemical abnormality is the 1-alpha hydroxylation of 25OH vitamin D (a process normally restricted to kidney) in lesional histiocytes which accompany these disease processes. This endogenous from of vitamin D intoxication is, in many series, the third most common cause of hypercalcemia, following primary hyperparathyroidism, 1,25OH vitamin D is decreased in hypoparathyroidism, pseudohypoparathyroidism, hypercalcemia of malignancy, renal failure, hyperphosphatemia, hypomagnesemia, and vitamin D-dependent rickets type 1
Sample: Serum, fasting & separate in glass tube