Normal range: Negative

Comment: Auto-antibodies against neurological organs are associated with different neoplasms. Their recognition is essential in their diagnosis

:Anti-Hu, Anti-Ri, Anti-Yo

Para-neoplastic syndrome: Neurological disorders secondary to malignancy can manifest in patients long time before their malignancy is discovered. Patients can manifest with Cerebellar ataxia, encephalomyelitis, myoclonus, or sensory neuropathy. Detection of neuronal antibody: Anti-Yo (antibody against Cerebellar Purkinje cells), Anti-Hu, Anti-Ri (against neuron nuclei) are strongly associated with this syndrome

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