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Normal range: Negative

Comment: This assay may provide support in the differential diagnosis between Grave’s disease and toxic nodular goiter, and may also be used to monitor the role of anti thyroid drugs. Despite the importance of the thyrotropin receptor antibody (TRAB) in the pathogenesis of Grave’s disease, the test is not often used in the clinical management of patients. TRAB is probably most helpful in patients with infiltrative ophthalmopathy or dermopathy without overt hyperthyroidism. In such situations, correct diagnosis

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requires correlation of physical findings, imaging studies, and laboratory tests

Sample: serum