Author Archives: د.حسام أبو فرسخ

(Respiratory Synctial Virus (G/M

Normal range: Negative

Comment: Detect specific RSV antibody in patients suspected of having RSV. In a primary infection, RSV-specific IgM appears after 5-8 days and persists for several weeks. Detectable increases in RSV- specific IgG anti body titers occur 2-4 weeks after symptomatic infections. Thus, during an acute infection, serology is less sensitive than direct antigen detection or cell culture method

Sample: serum

Rapid Plasma Reagin (RPR) Test

Normal range: Negative

Comment: RPR is a screening test for syphilis and detects antibodies to cardiolipin, cholesterol, and lecithin, also called reagin. Such antibodies usually develop after 4-6 weeks of initial infection, peak during the secondary phase of disease, and then decrease with time. They also decrease and usually disappear with treatment

Sample: serum

(Quadruple test (AFP, E3, BHCG, & Inhibin

Comment: The AFP, BHCG, uE3, & Inhibin A (quadruple test) is a screen used to help predict the risk of certain birth defects including Down syndrome and neural tube defects (NTD’s). The quadruple screen may pick up more at-risk patients than the double screen (AFP/hCG) or the triple screen (AFP/hCg/uE3) and has higher sensitivity than either one

Sample: Serum, LMP, age, weight, birth date, number of embryos

(Pyrlinks-D (Deoxy pridinoline

Comment: The major roles of biochemical markers of bone remodeling are as monitors of response to therapy. These markers can also be used to evaluate bone resorption (eg, in osteopenia, osteoporosis); identify patients at high risk of fracture; assess patients with carcinoma as markers of bone metastasis as well as indicators of response to therapy

Sample: Urine, early morning sample

(PTH (Parathyroid Hormone

Normal range: 13-54 pg/mL

Comment: Intact parathyroid hormone is more stable in EDTA plasma than in serum. Increased in hyperparathyrodism. Level usually low in non-hyperparathyroid causes of hypercalcaemia

Sample: EDTA tube or Serum, fasting, under ice

(Prothrombin time (PT

Normal range: 12-16 seconds

INR normal value: 1

INR therapeutic range: 2-3

Comment: Prothrombin time is prolonged by oral anticoagulant therapy, liver disease, malabsorption, DIC and congenital Factor II, V, VII, and X deficiencies. Results are reported as INR for oral anticoagulant control, an INR of between 2.0 and 4.0 is recommended, depending on the clinical condition

Sample: Citrated plasma

Protein, total serum

Normal range: 6.2-8.0 g/dL

Comment: Increased in hyperimmunoglobulinemia (polyclonal or monoclonal gammopathies). Also raised in dehydration and paraproteinemia. Decreased in nephrotic syndrome, severe liver disease, acute burns, malabsorption syndrome, malnutrition and hypogammaglobulinemia

Sample: Serum

Protein, 24 hr urine

Normal range: Up to 100 mg/24 hr

Comment: Proteinuria is present in glomerular or tubular disease. Massive proteinuria indicates that the disease is of glomerular origin. Also increased in nephrotic syndrome, diabetic nephropathy, myeloma kidney, multiple myeloma

Sample: 24hr urine


Protein, body fluids

:Normal range

Transudates  : <2.0 g/dL

Exudates       : >2.0 g/dL

Comment:Testing is done to determine whether a fluid is a transudate or an exudate

Sample: Body fluids