:Normal range
Child: 50-90 mL/min
M : 98-156 mL/ min
F : 95-160 mL/ min
Comment: Used to evaluate renal function, estimate glomerular filtration rate (GFR), follow possible progression of renal disease and adjust dosages of medications in which renal excretion is pivotal (e.g: aminoglycosides, methotrexate, cisplatin). Values of creatinine clearance are raised in exercise and pregnancy and are higher in males than in females. Low values are found in renal damage or renal circulatory insufficiency
Sample: serum and 24 hr urine