Normal range: Normal CSF has no demonstrable oligoclonal bands

Comment: Oligoclonal CSF bands contribute to the diagnosis of inflammatory and autoimmune disease of the CNS. In particular, they are found in 83% to 94% of subjects with clinically definite multiple sclerosis and in 100% of patients with subacute sclerosing panencephalitis (SSPE), and in other degenerative states as well (eg, presenile dementia). SSPE maybe the result of long-standing measles infection. With widespread measles vaccination, it has been nearly eradicated

Sample: Serum, CSF

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