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Normal range: 4.3-27 ng/mL

Comment: Estrtiol is an estrogen but less poternt than Estradiol. In pregnancy, both

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fetus and placenta are involved in biosynthesis of Estriol , which is secreted into maternal circulation, excreted in urine and serves as a sensitive indicator of fetoplancental status. Serial determination are more meaningful and a continuous fall during three consecutive days is Associated with fetal distress. Estriol levels during pregnancy are influenced by many other factors than fetal well –being

Sample: Serum, state LMP