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For myasthenia Gravis Acetyl cholinesterase
For familial polyposis coli Adenomatous polyposis coli
For adalin def. Adhalin
Liver disease; histiocyte marker Alpha-1- antitrypsin
Hepatocellular carcinoma and germ cell tumors Alpha-Fetoprotein
Lymphoma, some stromal tumors BCL2
Germ cell tumors B-HCG
Detect metastatic carcinoma to breast origin (Brst-2 (GCDFP-15
Detect metastatic carcinoma to ovarian origin CA125
Positive in medullary thyroid carcinoma Calcitonin
For mesothelioma Calretinin
Lymphoma panel CD23
Part of lymphoma panel CD10
Plasma cells CD138
Hodgkin’s disease marker (CD15 (Reed- sternberg cells
B-cell marker CD19
B-cell lymphomas CD20, B- cell
T-cell lymphomas CD3
Hodgkin’s marker, Alk marker CD30
Vascular tumors CD34
T-cell helper CD4
In Bronchioalveolar lavage CD4/CD8 ratio
Part of Lymphoma panel CD45 LCA
Small lymphocytic lymphoma CD5
T-cell supressor CD8
Ewing’s sarcoma CD99
GI tumors (CEA (CD66e
Neuroendocrine tumors Chromogainin A
Gastrointestinal stromal tumors marker C-kit
Mantle cell lymphoma Cyclin D1
Breast, lung, ovary, endometrium, pancreas Cytokeratin7
For carcinoma Cytokeratin, pan
In GI tumors Cytokeratin 20
Squamous and transitional cell carcinoma Cytokeratin HMW
For special carcinoma Cytokeratin LMW
   (Cytomegalo virus (CMV
Duchenne muscular dystrophy (Dystrophin (on muscle tissue
Latent membrane EBV EBV
Muscle dystrophy Emerin
To detect response to Tamoxifen Estrogen and progesterone receptors
Positive in astrocytic tumors GFAP
To detect herceptin response Her-2-neu
   Herpes simplex
glomerulonephritis and skin disease Immunoglobulin A, M, G
For lymphoma Kappa
For lymphoma Lambda
Congenital myopathy Merosin-Laminin
Mesothelioma (Mesothelin (CAK1
To detect resistance to chemotherapy Multi-dug resistant protein
Muscle marker Muscle specific actin
Myeloid leukemia, granulcytic sarcoma Myeloid BM 1
Rhabdomyosarcooma marker Myo D1
Molecular evidence of dysplasia; useful prognostic marker for tumor P53 Tumor suppressor gene
   (Parvovirus (B19
Seminoma (Placental Alkaline Phosphatase (PLAP
To detect metastatic prostate carcinoma Prostatic Specific Antigen
For clear cell renal cell carcinoma Renal cell Carcinoma
Neural tumors, melanoma S-100
Neuroendocrine tumors Synaptophysin
Lymphoblastic lymphoma TdT
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