:Normal range

 1-2wk after dose: <2.3 nmol/L

 72hrs after dose: < 100

If it exceeds these levels, then higher doses of leucovorin or extended rescue nmol/L

 1-2wk after dose : <2.3

 72hrs after dose: < 100

If it exceeds these levels, then higher doses of leucovorin or extended rescue

Comment: anti-neoplastic agent used in the treatment of many solid tumours, non-Hodgkin’s lymphoma and juvenile acute lymphoblastic leukaemia. Also used for some cases of psoriasis

Sample: Serum, state time of last dose

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