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Normal range: 350-1300 mOsm/Kg

Comment: Urine osmolality is use to evaluate the concentrating ability of the kidneys (e.g., in acute and chronic renal failure), electrolyte and water balance, renal disease, syndrome of inappropriate ant diuretic hormone secretion (SIADH), diabetes, dehydration, and amyloidosis. It is sometimes used in addition to urine analysis when the patient has been administrated radiopaque substances or has glycosuria or proteinuria. Estimation of urinary ammonium concentration and detection of increased osmolarity due to unusual molecules are possible using the urine osmolal gap. Osmolality is desirable in examination of neonatal urine when protein or glucose is present

Sample: Urine