Normal range: FPSA: 0.05-0.25 ng/mL
Comment: The free PSA: total PSA ratio is a useful screening test for identifying men with equivocal laboratory or physical findings who may benefit from prostate biopsy. This group includes those with mildly elevated total PSA (4-10 ng/mL) or those with enlarged prostate volumes detected by ultrasound. A high risk of carcinoma exists when the percentage of free PSA is very low cancer occurring in 55% of individuals with levels of 0% to 10% cancer risk was 5% to 9% when concentrations were > 25%. Its use in monitoring and determining prognosis of men with prostate carcinoma has not been established. A role in prostatic intraepithelial neoplasia is described
Sample: Serum