المختبرات الطبية الأولى

Venous thrombosis is among the three most common cardiovascular diseases affecting about 1:1000 individual each year. Thrombosis risk is determined by genetic risks, in addition to other factors surgery, age, pregnancy, contraceptives

We would like to announce that we have an updated profile of causes of thrombosis

Factor V leiden (by PCR): is most common point mutation in our population that causes venous thrombosis (20-60%) of the cases

Factor II (prothrombin factor by PCR): a gene defect that causes elevated plasma prothrombin and causes vein thrombosis by 3-5 folds

Homocysteine gene (By PCR): Hyperhomocysteinemia is caused by a defect in an enzyme 5,10-methylenetetrahydrofolate (MTHFR). This enzyme defect is common (5-20%) of the cases

Anti-Thrombin III deficiency, Protein S deficiency and protein C deficiency: All these proteins can affect thrombosis susceptibility

Anti-phospholipid, anti-cardiolipin and lupoid anticoagulant: cause venous thrombosis and can cause repeated abortions in pregnant ladies

All of the above thrombosis factors are responsible of over 90% of genetic diseases for thrombosis. Requesting the full Thrombosis Profile is essential in the management of all these cases

We in the First Medical Lab are dedicated to bring the best of Laboratory medicine to clinical practice in Jordan

Dr. Hussam Abu-Farsakh

American Board of Anatomic & Clinical Pathology, and Cytopathology

 

“Circular” is a periodic circular that distributed to clinician informing them about new and important tests available at First Medical Laboratory. All information listed are supported by recent literature