Normal range: 200-1000 pg/mL
Comment: Used to evaluate B12 and folic acid deficiencies, alcoholism, prenatal care malabsorption and neurological disorders
Increased during B12 therapy, myeloproliferative disorders chronic renal failure, diabetes, leukocytosis, polycythemia vera, some carcinomas, and rarely in primary hepatic carcinoma. Reduced in pernicious anemia, certain malnutrition and malabsorption states, megaloblastic anemia, congenital disorders and pregnancy
Sample: serum