Author Archives: د.حسام أبو فرسخ

Triglycerides

Normal range: 40-160 mg/dL

Comment: Increased in familial pre-beta hyperlipidaemia (Fredricksonn type IV), familial combined hyperlipidaemia (Fredrickson type IIb), familial type V hyperlipidaemia, familial dyslipidaemia (type III or broad-beta type and secondary hyperlipidaemia e.g. diabetes, obesity alcoholism etc

Sample: Serum, 12-14 hrs fasting

(Treponema Pallidum Hemagglutination (TPHA

Normal range: Negative

Comment: A more sensitive and specific test than the VDRL in the diagnosis of syphilis and used for confirming positive results obtained by screening tests. As false positive are very uncommon, a positive TPHA test is strong evidence of past or present treponemal infection

Sample: Serum, CSF

Transferrin

Normal range: 200-400 mg/dL

Comment:Increased: iron deficiency. Decreased: chronic disease, sideroblastic anemia; hemochromatosis

Sample: Serum

(Toxoplasma (IgG/ IgM

Normal range: Negative

Comment: Useful in the investigation of glandular fever-like syndromes, ophthalmic disease and unexplained fetal death. IgG titers suggest present or past infection; IgM tests are needed for better definition of present exposure. Only rising titers of positive IgM indicate current infection, because IgM indicate current infection, because IgM may stay for long periods after infection. Borderline results should be repeated in 2-3 weeks and positive results interpreted according to clinical findings

Sample: serum

(TORCH (G/M) TOXO, HSVI&II, RUBELLA, CMV (G, M

Normal range: Negative

Comment: Screening investigation for infants suspected of congenital or neonatal infection due to toxoplasma, rubella, Cytomegalovirus or herpes simplex. Positive results associated with intrauterine or current infection confirmed by IgM positive antibody test results

Sample: Serum

Tobramycin

:Normal range

Peak level : 8-10 m/mL

Trough level : 1-2 m/mL

Comment: Tobramycin is an Aminoglycoside. It is used in the treatment of

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G-ve infections and septicemia

Sample: Serum

Tissue Transglutaminase IgA antibody

Comment: Very usefule maker for

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celiac disease with high sensitivity and specificity

Sample: serum

Thyroxine, Total T4

Normal range: 5-10 mg/dL

Comment: High levels found in hyperthyrodism and low levels in primary or secondary hypothyyroidism. Value is influenced by the level of carrier proteins, e.g. thyoxine (Free TT4) is the preferred test

Sample: serum

(Testosterone (F

:Normal range

Age Male——-Age Female—————-
 0.9-3.2pg/mL      19-29                19-41
 0.8-3.0pg/mL      30-39                18-39
 0.6-2.5pg/mL      40-49                16-33
 0.3-2.7pg/mL      50-59                13-31
 0.4-2.0pg/mL      60-69                11-26
 0.2-2.0pg/mL      70-79                9-25

Comment: Free testosterone levels are valuable for investigating patients with hirsutism, loss of libido and male hypogondism. It is independent of changes in concentrations of the principal testosterone transport protein, sex hormone-binding globulin. Measurements of free testosterone may be more appropriate than measurements of total testosterone. It is independent of changes in concentrations of the principal testosterone transplant protein, sex hormone-binding globulin. Low values may be found in male infertility due to hypogonadism. High levels may indicate an adrenocortical tumor, adrogen-secreting ovarian tumor or pituitary overproduction of ACTH

Sample: Serum, state, sex, age

(Testosterone (T

:Normal range

M: 20-49 yrs: 270-1,734 ng/dL 50yrs : 212-755 ng/dL<

F: Ovulating : 63-120 ng/dL

Oral contraceptive : 54-71 ng/dL

Post-menopausal : 49-113 ng/dL

Comment: Total testosterone measurements have traditionally been used to help screen for hirsutism. Serum concentrations of testosterone in both sexs during the first week of life average about 25 ng/dL. Conditions such as hypogonadism. Hypopituitarism, orchiectomy, estrogen therapy, and some cases of Klinefelter’s syndrome are associated with decreased levels of testosterone. Levels increase from puberty to adult

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values, and related to pubertal stage rather than chronological age

Sample: Serum, state, sex, age