Author Archives: د.حسام أبو فرسخ

(B1 (Thiamin

(Normal range: 9-12 mmol/h/mL (150-200 U/L

Comment: Beriberi is the disease resulting from thiamine deficiency. The cause for deficiency include inadequate intake due to diets largely dependent on milled, nonenriched grains, such as rice and wheat, or to the ingestion of raw fish containing microbial thiaminases, which hydrolytically destroy the vitamin in the gastrointestinal tract. Tea may contain antithiamine factors that have been detected in certain other plant extracts. Chronic alcoholism is common contributor to deficiency in that there is not only a low intake of thiamine (and other B vitamins), but but also impaired absorption and storage

Sample: Serum, 3ml, fasting

(Asparate Aminotransferase (AST, GOT, SGOT

:Normal range

M: up to 37 IU/L             up to 0.62 mkat/L

F: up to31 IU/L               up to 0.52 mkat/L

Comment: Markedly raised values are found following myocardial infarction and in viral or toxic hepatitis, modest elevation is found with cholestasis, alcoholism, hepatic malignancy, chronic hepatitis, some skeletal muscle diseases and after muscle trauma

Sample: Serum

Apo-E

:Normal range

Comment: This test is used to evaluate abnormal lipid metabolism associate with coronary artery disease, study predisposing factors to the development of Alzheimer disease (AD), and aid in the differential diagnosis of AD

Sample: EDTA, whole blood

Apo lipo protein B

Normal range: 0.58-1.38 g/L

Comment: Apolipoprotein–B is the main structural component of Low Density Lipoprotein (LDL). Elevated levels indicate an increased atherogenic risk. This test is usefully combined with Apo-A1 ratio. This ratio is widely considered to provide the best discrimination of subjects with atherogenic risk, especially when used in conjunction with Lp(a) levels. The optimal ratio is less than 1.6:1

Sample: Serum, fasting, 14hr

Apo lipo protein A

Normal range: 0.73-1.69 g/L

Comment: Apolipoprotein A1 is the main structural component of high Density lipoprotein (HDL) and is thought to be the active anti-atherogenic component. Consequently Apo-A1 may show better discrimination of atherogenic at risk subjects than does HDL cholesterol measurement

Sample: Serum, fasting, 14hr

Anti-Ku Antibodies

Normal range: Negative

Comment: Aid the differential diagnosis of diffuse scleroderma (Progressive systemic sclerosis). The antibody is found in up to a quarter of individuals who have idiopathic Raynaud phenomenon. It is also seen in inflammatory myositis

Sample: serum