Introduction: This is a cell surface glycoprotein, strongly expressed in mesothelial cells, benign or malignant :Clinical Use -1 Confirming the diagnosis of Mesothelioma ( the only marker available as positive confirmation -2 Identying atypical cells in the body fluid (e.g: pleural or peritoneal fluid) whether of mesothelial origin or Fantastic oxidizes. gives. It loans online… Read More: (Mesothelin (CAK1 »
Microvillous inclusion disease (MID) : Familial Microvillous Atrophy is a cause of intractable diarrhea in infancy. The light microscopy picture is usually normal and that may account for many cases that may passed unnoticed. Its diagnosis is used to be troublesome in the past. Usually the patient may have more than one time biopsy due… Read More: Microvillous Inclusion Disease and CD 10 »
Colon carcinoma is known to have a familial tendency. 15% of patients with colorectal carcinoma have hereditary syndrome called: Hereditary Non-Polyposis Colorectal Caner (HNPCC). Patients that have colon carcinoma below the age of 50 years are likely to have this syndrome than older patients. The genetic alterations in this case includes mutations in Mismatch Repair… Read More: Molecular Studies and Colon Carcinoma »
Introduction: MRP is a surface glycoprotein that is expressed in the cell surface of many tumor cells and contributes to the tumor resistance, by moving chemotherapy (efflux) out of the cells Clinical use: In acute leukemias, that are secondary (to Myelodysplasia or to Alkylating agents) or that occur in the elderly, the chance of expressing… Read More: Multi-Drug resistant protein (MRP) and acute leukemia »
The advances made in muscle biopsy in Jordan, now, are becoming able to diagnose many of the muscle types of dystrophies with certainty Introduction: the muscle membrane is peculiar among other cell membranes by having complex of proteins that are attached to the muscle membrane, that are very important for its integrity and action. The… Read More: MUSCULAR DYSTROPHIES DIAGNOSIS IN JORDAN »
Myocarditis can be a fatal disease and can be caused by several viruses and bacterial disease. Its exact diagnosis, in many instances, can help in the treatment The Myocarditis profile contains a list of viruses and bacteria that can cause Myocarditis :The list includes the followings Mumps virus– Adenovirus type 3– (Influenza virus type A… Read More: Myocarditis profile »
Nerve disease can be studies in details in our lab to detect meylin and axonal disoders :We perform the following special stains and special tests Holmes method for nerve cells and fibers- Bielschowsky method for neurofibrils- Luxol fast blue for myelin- Electron microscpy for detail of nerve axons and myelins :Material requied A piece of… Read More: Nerve biopsy »
Auto-immune hepatitis (AIH) has a clinical and histologic criteria with well established diagnostic scores. It has predilection for females. Liver enzymes show elevation of aminotransferease more than alkaline phosphatase. Increased serum gamma globulin, presence of smooth muscle antibody and LKM-1, (with usually negative anti-mitochondria antibodies) are usually part of diagnostic criteria. AIH patients have usually… Read More: (New lab markers for Autoimmune hepatitis (LC-1 and SLA/LP »
Diagnosing T.B could be difficult sometimes and requires more tests. Relying on finding Acid Fast Bacilli is usually not reliable in many cases. PCR for T.B also has a limitation and can not be performed on the blood. FDA approved 2 new tests for T.B. The first one is �anda-tb�. This test is relying on… Read More: New Tests For Tuberculosis in The Blood and In Infected… »
New tests in neurology We are proud in the �First Medical Lab� to launch our �Neurology Testing Center� to be the first in the middle east specialized in testing different neurological diseases that affect our population. These tests will help the clinician in the diagnosis of different types of neuropathies, muscle diseases, dementia, blindness and… Read More: New tests in neurology »