Normal range: Negative
Comment: The factor II prothrombin G20210A mutation is a common genetic risk factor for thrombosis and is associated with elevated prothrombin levels. Although homozygosity is rare, inheritance of two 20210A alleles would increase the risk for developing thrombosis. If a patient heterozygous for both the prothrombin G20210A and the factor V Leiden mutation, the combined heterozygosity leads to an earlier onset of thrombosis and tends to be more sever than single–gene heterozygotes
Sample: EDTA whole blood