Author Archives: د.حسام أبو فرسخ

(Iron binding capacity total (TIBC

Normal range: Adult           : 250-410 mg/dL; Infant        : 100-400 mg/dL Comment: Increased in liver damage, hemolytic anemias, hemochromatosis and in iron deficiency. Reduced in acute and chronic infections, nephrotic syndrome, cirrhosis, hemorrhage, hypothyroidism, thalassemias, and uremia Sample: serum

Immunohistochemistry

:Comment For myasthenia Gravis Acetyl cholinesterase For familial polyposis coli Adenomatous polyposis coli For adalin def. Adhalin Liver disease; histiocyte marker Alpha-1- antitrypsin Hepatocellular carcinoma and germ cell tumors Alpha-Fetoprotein Lymphoma, some stromal tumors BCL2 Germ cell tumors B-HCG Detect metastatic carcinoma to breast origin (Brst-2 (GCDFP-15 Detect metastatic carcinoma to ovarian origin CA125 Positive… Read More: Immunohistochemistry »

IgG Subclasses

:Normal range IgG1: 65 %, IgG2: 25 %, IgG3: 6%, IgG4: 4% (IgG Subclass levels (mg/dL IgG4 IgG3 IgG2 IgG1 Age 6-63 9-62 30-140 190-620 0-1 y 4-43 11-98 30-170 230-710 1-2 y 3-120 6-130 40-240 280-830 2-3 y 5-180 9-160 50-310 350-810 3-6 y 11-620 13-320 30-630 270-1740 > 6 y Comment: Approximately 80%… Read More: IgG Subclasses »

Hydroxyprogesterone

:Normal range M: 0.42-3.5 ng/mL F: *Follicular phase: 0.20-2.6 ng/mL Luteal phase: 0.28-4.0 ng/mL* Oral contraceptives: 0.09-1.7 ng/mL* :Post-menopausal* o        No hormone therapy: 0.11-1.2 ng/mL o        With hormone therapy: 0.08-0.93 ng/mL Comment: Used in the investigation of congenital adrenal hyperplasia. Increased in C-21-hydroxylase enzyme deficiency, some cases of ovarian or adrenal neoplasms, and in congenital adrenal… Read More: Hydroxyprogesterone »

Inhibin A & B serum

:Normal range Inhibin A  pg/mL 5.46-28.16      : Early follicular phase 0-4 day of LMP  pg/mL 7.87-34.54      : Mid follicular phase 5-10 day of LMP  pg/mL 19.49-102.28  : Late follicular 11-13 day of LMP pg/mL 49.92-155.48  : Day of ovulation 14 day of cycle  pg/mL 35.93-132.68  : Early luteal phase 15-17 day of LMP  pg/mL 13.15-159.55  : Mid… Read More: Inhibin A & B serum »

(Insulin-like growth factor binding protein–3 (IGFBP-3

:Normal range (F:(mg/L (M:(mg/L (Age(y (F:(mg/L (M:(mg/L (Age(y 1.45-5.69 1.45-4.75 22-23 0.66-2.51 0.9-1.79 0-1 1.51-4.4 1.15-4.3 24-25 0.843.77 1.12-2.33 2-3 1.38-4.7 1.24-5.18 26-27 1.32-3.6 1.16-3.13 4-5 1.19-5.43 1.23-4.27 28-29 1.21-4.66 1.32-3.38 6-7 1.29-4.06 1.29-4.06 30-34 1.58-3.99 1.35-3.94 8-9 1.5-3.44 1.5-3.44 35-39 1.93-5.5 1.53-5.02 10-11 1.33-3.6 1.33-3.58 10-44 1.78-6.08 1.73-5.11 12-13 1.44-2.8 1.44-2.75 45-49 2.02-5.4 1.9-6.4… Read More: (Insulin-like growth factor binding protein–3 (IGFBP-3 »

Iron

Normal range: 60-160 mg/dL Comment: IgE levels maybe raised in atopic allergies. RAST and MAST allergy tests are unlikely to be positive if total IgE is less than 30 IU/l in adults Sample: serum

Ionized calcium

Normal range: 1.08-1.31 mmol/L Comment: Ionized calcium reflects the physiological active function of total calcium. Increased in primary hyperparathyrodism, excess intake of vitamin D ectopic PTH-producing tumors. Elevation maybe seen even when total Ca is normal.Decreased in hypoparathyrodism, vitamin D deficiency and magnesium deficiency Sample: Heparin, vacationer, send immediately

(Insulin-like growth factor 1(IGF-1

Normal range: 0.54-5.54 ng/mL Comment: Somatomedin-C is a co-factor for growth hormone and can therefore be used in the investigation of patients with growth problems Sample: 2 ml serum, fasting & freeze immediately

Insulin

Normal range: Up to 165 pmol/L Comment: For diagnosis of the cause of hypoglycaemia. The test should be done in conjunction with a glucose determination in the fasting state Sample: serum