Author Archives: د.حسام أبو فرسخ

Anti Ds DNA Antibody

Normal range: Negative Comment Autoimmune anti – double stranded DNA antibody levels are usually significantly elevated in active SLE. Specificity for SLE is high and correlates with disease activity and with the occurrence of glomerulonephritis and it is a good marker to monitor the progression (increasing levels) and remission (decreasing levels) of SLE Sample: serum

Anti Adrenal glands Ab

Normal range: Negative Comment: Used to evaluate adrenal insufficiency and Addison’s disease. Serum antibodies to adrenal cortical cells, usually of all three zones, are seen in 60 % of patients with idiopathic Addison’s disease. They are also present in patients with fungal, tuberculous, or metastatic destruction of the adrenals. Antiadrenal antibodies can be present in… Read More: Anti Adrenal glands Ab »

(Anti Gangliosides Ab (G/M

Normal range: Negative Comment: Antibodies against ganglioside are found in various types of peripheral neuropathy. These include Guillain-Barrie’ syndrome, Miller Fisher syndrome (a variant of Guillain-Barrie’ with descending neuropathy). Also seen in Motor neuron disease and chronic inflammatory demyelinating polyneuropathy   :Test profile :The following antibodies are examined GM1      : Monosialoganglioside GM1 GM2      : Monosialoganglioside… Read More: (Anti Gangliosides Ab (G/M »

Androstenedione

:Normal range Children: 0.1-0.5 ng/mL Male: 0.6-2.7 ng/mL Female: 0.5-2.7 ng/mL Comment: There is diurnal variation. Useful in diagnosis and management of congenital adrenal hyperplasia. Also of value in theinvestigation of hirsutism or virilism in females, when high levels may indicate either an adrenal cortical tumor or hypersecretion of ACTH Sample: serum

Amylase, urine

:Normal range 24hr urine: Results are in relation to the volume collected (Spot urine: < 460 IU/L    (< 7.67 mkat/L Comment: Raised levels parallel serum amylase unless there is renal failure. When the plasma enzyme is bound to a high molecular weight carrier. (macroamyasaemia), urine amylase is normal. Urine amylase may remain elevated for… Read More: Amylase, urine »

Amylase, serum

Normal range: up to 220 u/l Comment: Useful in diagnosis of acute pancreatitis; desirable to support the clinical significance of elevated serum lipase. Serum amylase is used to work up abdominal pain, epigastric tenderness, nausea, and vomiting, findings which characterize acute pancreatitis as well as acute surgical emergencies such as gastrointestinal perforation (eg, peptic ulcer… Read More: Amylase, serum »

Amylase, body fluids

Normal range: Ascetic & pleural fluids amylase activity are identical to, or slightly less than, serum activity Comment: Ascetic fluidamylase level is increased in pancreatitis, intestinal obstruction or infraction, strangulated bowel, perforated hollow viscus, biliary tract disease, carcinoma of ovary, ruptured ectopic pregnancy, disseminated secondary neoplasm, peritonitis, pancreatic cyst or pseudocyst. Pleural fluid amylase levels… Read More: Amylase, body fluids »

Ammonia, blood

(Normal range: 0.2-0.8 mg/ml (12-47 mmol/L Comment: Ammonia and alpha- ketoglutarate with NADH yield glutamate; glutamate and ammonia yield glutamine. Cerebrospinal fluid glutamine levels are useful in hepatic encephalopathy and with Reye syndrome. In the HHH syndrome, hyperammonemia is intermittent; it presents in infancy often, but symptoms can be delayed. Metabolic acidosis with ketosis are… Read More: Ammonia, blood »